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Home >> Antibodies >> SAT1 Antibody / Spermidine/spermine N(1)-acetyltransferase 1 [Discontinued, view alternative antibodies]

SAT1 Antibody / Spermidine/spermine N(1)-acetyltransferase 1 [Discontinued, view alternative antibodies] [clone CPTC-SAT1-3] (V7346)

  Catalog No Formulation Size Price (USD)  
Image V7346-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7346-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7346SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated
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Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using SAT1 antibody. These results demonstrate the foremost specificity of the CPTC-SAT1-3 mAb.
Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Availability Discontinued
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a, kappa
Clone Name CPTC-SAT1-3
Purity Protein G affinity chromatography
UniProt P21673
Localization Cytoplasmic
Applications ELISA (order BSA/sodium azide-free format for coating) :
Limitations This SAT1 antibody is available for research use only.
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Description

Spermidine/spermine N1-acetyltransferase 1 (SAT1 or SSAT1) is the key regulatory enzyme in the catabolism of polyamines, catalyzing acetylation of spermidine or spermine to generate N1-acetyl spermidine or N1-acetyl spermine, and N1, N12-diacetylspermine. The cellular level of SAT1 is normally extremely low, but it is induced rapidly by a variety of stimuli, including polyamines, polyamine analogs, toxic chemicals, certain drugs, and growth factors. Downregulation of SAT1 has been reported in Epstein-Barr virus positive Burkitt's lymphoma cells.

Application Notes

Optimal dilution of the SAT1 antibody should be determined by the researcher.

Immunogen

Recombinant human protein was used as the immunogen for this SAT1 antibody.

Storage

Store the SAT1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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