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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex.
The stated application concentrations are suggested starting amounts. Titration of the RUNX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 1-30 from the human protein was used as the immunogen for this RUNX2 antibody.
Store at 4oC for up to one month. For long term, aliquot the RUNX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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