- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
The RUFY3 gene, also called RUN and FYVE domain-containing protein 3 and Rap2-interacting protein x (RIPx), encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants.
Optimal dilution of the RUFY3 antibody should be determined by the researcher.
E. coli-derived recombinant human protein (amino acids M1-H469) was used as the immunogen for the RUFY3 antibody.
After reconstitution, the RUFY3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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