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Home >> Antibodies >> RNase L Antibody / Rnasel

RNase L Antibody / Rnasel (RQ6435)

  Catalog No Formulation Size Price (USD)  
Image RQ6435 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Flow cytometry testing of mouse HEPA1-6 cells with RNase L antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= RNase L antibody.
Flow cytometry testing of rat NRK cells with RNase L antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= RNase L antibody.
Western blot testing of mouse 1) lung and 2) RAW264.7 cell lysate with RNase L antibody. Predicted molecular weight ~83 kDa.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q05921
Applications Western blot : 0.5-1ug/ml
Flow cytometry : 1-3ug/million cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This RNase L antibody is available for research use only.
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Description

RNase L is an enzyme that in humans is encoded by the RNASEL gene. This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele.

Application Notes

Optimal dilution of the RNase L antibody should be determined by the researcher.

Immunogen

Recombinant mouse protein (amino acids E24-S735) was used as the immunogen for the RNase L antibody.

Storage

After reconstitution, the RNase L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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