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Home >> Antibodies >> RIPK3 Antibody

RIPK3 Antibody (F50171)

  Catalog No Formulation Size Price (USD)  
Image F50171-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F50171-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of RIPK3 antibody and Ramos lysate. Predicted molecular weight ~57 kDa.
IHC analysis of FFPE human lung carcinoma tissue stained with RIPK3 antibody
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q9Y572
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Limitations This RIPK3 antibody is available for research use only.
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Description

The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

Application Notes

Titration of the RIPK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 1-30 from the human protein was used as the immunogen for this RIPK3 antibody.

Storage

Aliquot the RIPK3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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