- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
RIG-I Antibody / DDX58 [clone ACEA-4] (RQ4812)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ4812 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | ACEA-4 |
| Purity | Affinity purified |
| UniProt | O95786 |
| Applications | Western blot : 1:500-1:1000 |
| Limitations | This RIG-I antibody is available for research use only. |
|
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Retinoic acid inducible gene I (RIG-I) is a 925 amino acid, interferon-inducible cellular DExD/H box RNA helicase that activates type I interferon (IFN), an important effector of the innate immune system that is sensitive to these dsRNA viruses. dsRNA is normally present in very low quantities in cells, so when a virus is present, the elevated levels of dsRNA act as a sign telling RIG-I to activate the production of IFN.
Optimal dilution of the RIG-I antibody should be determined by the researcher.
A synthetic peptide specific to human RIG-I was used as the immunogen for the RIG-I antibody.
Store the RIG-I antibody at -20oC.
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