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Home >> Antibodies >> RETN Antibody / Resistin

RETN Antibody / Resistin [clone RETN/4326] (V8900)

  Catalog No Formulation Size Price (USD)  
Image V8900-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V8900-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V8900SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated
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IHC staining of FFPE human spleen tissue with RETN antibody (clone RETN/4326). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human spleen tissue with RETN antibody (clone RETN/4326). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Western blot testing of human heart tissue lysate using RETN antibody (clone RETN/4326). Predicted molecular weight ~11 kDa.
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using RETN antibody (clone RETN/4326). These results demonstrate the foremost specificity of the RETN/4326 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Clone Name RETN/4326
Purity Protein A/G affinity
UniProt Q9HD89
Localization Secreted
Applications Western blot : 2-4 ug/ml
Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This RETN antibody is available for research use only.
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Description

The cysteine-rich, adipose tissue-specific, secretory factor resistin (resistance to Insulin) also known as ADSF, is a secreted hormone that potentially links obesity to diabetes. Resistin is rich in serine and cysteine residues and contains a unique cysteine repeat motif. Resistin and the resistin-like molecules share the characteristic cysteine composition and other signature features. Resistin-like expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation.

Application Notes

Optimal dilution of the RETN antibody should be determined by the researcher.

Immunogen

A portion of amino acids 19-108 was used as the immunogen for the RETN antibody.

Storage

Aliquot the RETN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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