- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Retinoblastoma Antibody / Rb1 [clone BHC-18] (RQ5140)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ5140 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | BHC-18 |
| Purity | Affinity purified |
| UniProt | P06400 |
| Applications | Western blot : 1:500-1:2000 |
| Limitations | This Retinoblastoma antibody is available for research use only. |
|
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The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [RefSeq]
Optimal dilution of the Retinoblastoma antibody should be determined by the researcher.
A synthetic peptide specific to human Retinoblastoma / Rb was used as the immunogen for the Retinoblastoma antibody.
Store the Retinoblastoma antibody at -20oC.
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