- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
TRIM29 Antibody Recombinant Rabbit MAb / Tripartite motif-containing protein 29 [clone TRIM29/9256R] (V5597)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V5597-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
|
|
V5597-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
|
|
V5597SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG, kappa |
| Clone Name | TRIM29/9256R |
| Purity | Protein A/G affinity |
| UniProt | Q14134 |
| Localization | Cytoplasm, Cell membrane |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml |
| Limitations | This TRIM29 antibody is available for research use only. |
|
Review this product on BioCompare and get a $20 Amazon gift card
|
Related Products
|
Tripartite motif-containing protein 29 is a TRIM family member encoded by the TRIM29 gene and is also widely known as ATDC or ataxia-telangiectasia group D complementing protein. The TRIM29 Antibody Recombinant Rabbit MAb TRIM29/9256R is developed to detect this epithelial-associated regulatory protein in research applications focused on DNA damage response and tumor biology. TRIM29 is located on chromosome 11q23 and differs from many other TRIM proteins in that it lacks a canonical RING domain while retaining B-box and coiled-coil motifs that mediate protein-protein interactions and scaffold functions.
TRIM29 functions as a regulatory adaptor protein and has been implicated in modulation of chromatin organization, transcriptional control, and cellular responses to genotoxic stress. It has been reported to interact with components of the p53 signaling pathway and other regulatory complexes that influence proliferation and apoptosis. Through these mechanisms, TRIM29 contributes to epithelial differentiation, stress signaling, and maintenance of genomic stability. Subcellular localization studies describe both cytoplasmic and nuclear distribution depending on cell type and physiologic context.
Expression of TRIM29 is enriched in epithelial tissues including pancreas, lung, skin, and gastrointestinal tract. In cancer research, altered TRIM29 expression has been observed in pancreatic, gastric, lung, breast, and bladder carcinomas. Its biologic role appears context dependent, with evidence supporting involvement in tumor progression or modulation of stress response pathways depending on tumor type. This tissue-specific behavior underscores its importance in epithelial transformation and oncogenic signaling networks.
As part of the tripartite motif protein family, TRIM29 participates in pathways that regulate protein stability and cellular stress adaptation. Investigation of TRIM29 expression supports research focused on epithelial integrity, DNA damage response mechanisms, and cancer-associated signaling biology. Clone TRIM29/9256R is a recombinant rabbit monoclonal antibody designed for specific detection of TRIM29 protein expression in diverse research settings.
Optimal dilution of the TRIM29 antibody should be determined by the researcher.
A recombinant fragment (within amino acids 1-200) of human TRIM29 protein was used as the immunogen for the TRIM29 antibody recombinant rabbit mAb TRIM29/9256R.
Aliquot the TRIM29 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Your bulk quote request has been submitted successfully!
Please contact us if you have any questions.
Powered by Bioz
