Synaptophysin Antibody Microarray Specificity Validated Clone SYP/4389R / SYP Microarray Specificity Validated Antibody [clone SYP/4389R] (V9165)

Synaptophysin Antibody Microarray Specificity Validated Clone SYP/4389R. Protein microarray specificity validation using the HuProt(TM) human protein microarray platform containing more than 19,000 full-length human proteins demonstrates selective recognition of the Synaptophysin / SYP target by monoclonal antibody clone SYP/4389R. Signal ranking analysis identifies SYP as the top-ranked protein on the array with a strong Z-score signal compared with other proteins tested, indicating preferential binding of the antibody to Synaptophysin. Additional proteins such as CD47 and FBXO2 show substantially lower signal intensity, further supporting the high specificity of this microarray specificity validated antibody. In HuProt(TM) microarray analysis, the Z-score represents the strength of antibody binding signal relative to the overall signal distribution on the array, expressed as standard deviations above the mean signal intensity. Targets are ranked according to their Z-scores, and the S-score represents the difference between consecutive Z-scores in the ranked list. The S-score therefore reflects the relative target specificity of the antibody for its intended antigen. The strong enrichment of the Synaptophysin signal and the clear separation from subsequent ranked proteins demonstrate the specificity of Synaptophysin Antibody Microarray Specificity Validated Clone SYP/4389R for the Synaptophysin protein during large-scale protein microarray screening.

Synaptophysin Antibody Microarray Specificity Validated Clone SYP/4389R. Immunohistochemistry analysis of FFPE human pancreatic tissue using Synaptophysin Antibody Microarray Specificity Validated Clone SYP/4389R. The monoclonal antibody clone SYP/4389R produces strong cytoplasmic staining in pancreatic islet cells consistent with Synaptophysin / SYP expression in neuroendocrine cells. Synaptophysin is a synaptic vesicle membrane glycoprotein widely used as a marker of neuroendocrine differentiation, and the observed granular cytoplasmic staining pattern aligns with the known localization of SYP within synaptic vesicles. Microarray specificity validation of clone SYP/4389R supports selective target recognition, helping confirm specific detection of Synaptophysin protein in immunohistochemistry analysis of formalin-fixed paraffin-embedded pancreatic tissue.