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Home >> Antibodies >> Recombinant StAR Antibody / Steroidogenic acute regulatory protein

Recombinant StAR Antibody / Steroidogenic acute regulatory protein [clone STAR/3915R] (V8972)

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  Catalog No Formulation Size Price (USD)  
Image V8972-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V8972-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V8972SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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IHC staining of FFPE human testicular carcinoma tissue with recombinant StAR antibody (clone STAR/3915R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human testicular carcinoma tissue with recombinant StAR antibody (clone STAR/3915R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant StAR antibody (STAR/3915R) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name STAR/3915R
Purity Protein A/G affinity
UniProt P49675
Localization Cytoplasm
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant StAR antibody is available for research use only.
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Description

Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone.It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.

Application Notes

Optimal dilution of the recombinant StAR antibody should be determined by the researcher.

Immunogen

A portion of amino acids 39-108 was used as the immunogen for the recombinant StAR antibody.

Storage

Aliquot the recombinant StAR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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