SOX10/Melanocytic Lineage Antibody [clone SOX10/2311R] (V3690)

IHC testing of FFPE melanoma with SOX10/Melanocytic Lineage antibody (clone SOX10/2311R). Required HIER: boil sections in pH 9 10mM Tris with 1mM EDTA for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.

SDS-PAGE analysis of purified, BSA-free SOX10/Melanocytic Lineage antibody (clone SOX10/2311R) as confirmation of integrity and purity.

Western blot testing of human COLO-38 cell lysate with SOX10/Melanocytic Lineage antibody (clone SOX10/2311R). Expected molecular weight: 50-58 kDa.

Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using SOX10/Melanocytic Lineage antibody. These results demonstrate the foremost specificity of the SOX10/2311R mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.