SRY-box 10/SOX10 Antibody [clone rSOX10/1074] (V3563)

IHC testing of FFPE human melanoma with SRY-box 10/SOX10 antibody (clone rSOX10/1074). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min followed by cooling at RT for 20 min.

SDS-PAGE analysis of purified, BSA-free SRY-box 10/SOX10 antibody (clone rSOX10/1074) as confirmation of integrity and purity.

Western blot testing of human COLO-38 cell lysate with SRY-box 10/SOX10 antibody (clone rSOX10/1074). Expected molecular weight: 50-58 kDa.

Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using SRY-box 10/SOX10 antibody. These results demonstrate the foremost specificity of the rSOX10/1074 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.