Recombinant SMMHC Antibody / Smooth Muscle Myosin Heavy Chain [clone MYH11/7087R] (V9683)

Recombinant SMMHC Antibody Prostate IHC. Immunohistochemical staining of FFPE human prostate tissue demonstrates Smooth Muscle Myosin Heavy Chain expression using recombinant SMMHC antibody clone MYH11/7087R. SMMHC, encoded by the MYH11 gene, is a highly specific marker of differentiated smooth muscle and myoepithelial cells. Strong cytoplasmic staining highlights the smooth muscle stroma surrounding prostatic glands, while the glandular epithelium remains largely negative. This characteristic distribution reflects the abundant contractile smooth muscle component of the prostate and underscores the utility of SMMHC as a marker of smooth muscle differentiation. Heat induced epitope retrieval was performed by boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 20 minutes followed by cooling prior to staining. These results support the utility of SMMHC Antibody for studies of prostate histology, smooth muscle biology, and diagnostic pathology.

Recombinant SMMHC Antibody Smooth Muscle IHC. Immunohistochemical staining of FFPE human smooth muscle tissue demonstrates robust expression of Smooth Muscle Myosin Heavy Chain using recombinant SMMHC antibody clone MYH11/7087R. SMMHC, encoded by the MYH11 gene, is a principal component of the contractile apparatus and one of the most specific markers of mature smooth muscle differentiation. Strong diffuse cytoplasmic staining is observed throughout bundles of spindle-shaped smooth muscle cells, consistent with the abundant expression of MYH11 in contractile tissues. Heat induced epitope retrieval was performed by boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 20 minutes followed by cooling prior to staining. These results support the utility of SMMHC Antibody for studies of vascular biology, smooth muscle pathology, and tissue differentiation.

SDS-PAGE analysis of purified, BSA-free recombinant SMMHC antibody (clone MYH11/7087R) as confirmation of integrity and purity.