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Home >> Antibodies >> Recombinant RPSA Antibody / 40S Ribosomal protein SA / Laminin Receptor 1

Recombinant RPSA Antibody / 40S Ribosomal protein SA / Laminin Receptor 1 [clone rRPSA/6333] (V8946)

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  Catalog No Formulation Size Price (USD)  
Image V8946-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V8946-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V8946SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recmousemono
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IHC staining of FFPE human skin squamous cell carcinoma with recombinant RPSA antibody (clone rRPSA/6333). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human skin squamous cell carcinoma with recombinant RPSA antibody (clone rRPSA/6333). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human cervical carcinoma tissue with recombinant RPSA antibody (clone rRPSA/6333). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human colon tissue with recombinant RPSA antibody (clone rRPSA/6333). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant RPSA antibody (clone rRPSA/6333) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG1, kappa
Clone Name rRPSA/6333
Purity Protein A/G affinity
UniProt P08865
Localization Cell Surface,Cytoplasmic, Nuclear
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant RPSA antibody is available for research use only.
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Description

Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.

Application Notes

Optimal dilution of the recombinant RPSA antibody should be determined by the researcher.

Immunogen

Recombinant full-length human RPSA protein was used as the immunogen for the recombinant RPSA antibody.

Storage

Aliquot the recombinant RPSA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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