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Home >> Antibodies >> Recombinant RBP-1 Antibody / Retinol Binding Protein 1

Recombinant RBP-1 Antibody / Retinol Binding Protein 1 [clone rRBP1/872] (V8050)

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  Catalog No Formulation Size Price (USD)  
Image V8050-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V8050-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V8050SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recmousemono
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IHC: Formalin-fixed, paraffin-embedded human hepatocellular carcinoma stained with recombinant RBP-1 (clone rRBP/872). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC: Formalin-fixed, paraffin-embedded human hepatocellular carcinoma stained with recombinant RBP-1 (clone rRBP/872). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant RBP-1 antibody (clone rRBP1/872) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG1, kappa
Clone Name rRBP1/872
Purity Protein G affinity chromatography
UniProt P09455
Localization Cytoplasmic
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant RBP-1 antibody is available for research use only.
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Description

Retinol Binding Protein 1 or Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. RBP1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.

Application Notes

Optimal dilution of the recombinant RBP-1 antibody should be determined by the researcher.

Immunogen

A recombinant full-length human protein was used as the immunogen for this recombinant RBP-1 antibody. This mAb recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment).

Storage

Store the recombinant RBP-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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