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Home >> Antibodies >> Recombinant PMEPA1 Antibody / TMEPAI

Recombinant PMEPA1 Antibody / TMEPAI [clone rPMEPA1/6422] (V9286)

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  Catalog No Formulation Size Price (USD)  
Image V9286-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V9286-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V9286SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recmousemono
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IHC staining of FFPE human prostate tissue with recombinant PMEPA1 antibody (clone rPMEPA1/6422). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human prostate tissue with recombinant PMEPA1 antibody (clone rPMEPA1/6422). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human colon carcinoma tissue with recombinant PMEPA1 (clone rPMEPA1/6422). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant PMEPA1 antibody (clone rPMEPA1/6422) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG1, kappa
Clone Name rPMEPA1/6422
Purity Protein A/G affinity
UniProt Q96W9
Localization Cell surface, Cytoplasm
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant PMEPA1 antibody is available for research use only.
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Description

PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.

Application Notes

Optimal dilution of the recombinant PMEPA1 antibody should be determined by the researcher.

Immunogen

Recombinant full-length human PMEPA1/TMEPAI protein was used as the immunogen for the recombinant PMEPA1 antibody.

Storage

Aliquot the recombinant PMEPA1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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