- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Recombinant PDCD1 Antibody / PD-1 / PD1 [clone PDCD1/7125] (V4042)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
V4042-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 519 | |
|
|
V4042-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 229 | |
|
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V4042SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 519 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Clone Name | PDCD1/7125 |
| Purity | Protein A/G affinity |
| UniProt | Q15116 |
| Localization | Cell surface, cytoplasm |
| Applications | ELISA : for coating order antibody without BSA : Immunohistochemistry (FFPE) : 1-2ug/ml |
| Limitations | This recombinant PDCD1 antibody is available for research use only. |
|
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PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
Optimal dilution of the recombinant PDCD1 antibody should be determined by the researcher.
A portion of amino acids 1-200 from the human protein was used as the immunogen for the recombinant PDCD1 antibody.
Aliquot the recombinant PDCD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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