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Home >> Antibodies >> Recombinant PAX7 Antibody

Recombinant PAX7 Antibody [clone rPAX7/9325] (V5518)

  Catalog No Formulation Size Price (USD)  
Image V5518-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 559
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V5518-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 259
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V5518SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 559
Microvalidated Recmousemono
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SDS-PAGE analysis of purified, BSA-free recombinant PAX7 antibody (clone rPAX7/9325) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Host Mouse
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG2b, kappa
Clone Name rPAX7/9325
Purity Protein A/G affinity
UniProt P23759
Localization Nucleus
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant PAX7 antibody is available for research use only.
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Description

The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

For additional information on PAX7 and its use in studying muscle stem and progenitor cell populations, see our PAX7 Antibody page.

Application Notes

Optimal dilution of the recombinant PAX7 antibody should be determined by the researcher.

Immunogen

A recombinant fragment (amino acids 301-505) of human PAX7 protein was used as the immunogen for the recombinant PAX7 antibody.

Storage

Aliquot the recombinant PAX7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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