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Home >> Antibodies >> Recombinant PAX7 Antibody

Recombinant PAX7 Antibody [clone rPAX7/9325] (V5518)

  Catalog No Formulation Size Price (USD)  
Image V5518-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5518-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5518SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
Microvalidated Recmousemono
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SDS-PAGE analysis of purified, BSA-free recombinant PAX7 antibody (clone rPAX7/9325) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG2b, kappa
Clone Name rPAX7/9325
Purity Protein A/G affinity
UniProt P23759
Localization Nucleus
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant PAX7 antibody is available for research use only.
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Description

The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Application Notes

Optimal dilution of the recombinant PAX7 antibody should be determined by the researcher.

Immunogen

A recombinant fragment (amino acids 301-505) of human PAX7 protein was used as the immunogen for the recombinant PAX7 antibody.

Storage

Aliquot the recombinant PAX7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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