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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).
Optimal dilution of the recombinant PAX7 antibody should be determined by the researcher.
A recombinant fragment (amino acids 301-505) of human PAX7 protein was used as the immunogen for the recombinant PAX7 antibody.
Aliquot the recombinant PAX7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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