- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
NAPSA Antibody / Secretory Pathway Antibody [clone rNAPSA/1239] (V3634)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V3634-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 100 ug | 559 | |
|
|
V3634-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 20 ug | 259 | |
|
|
V3634SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 | |
|
|
V3634IHC-7ML | Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only* | 7 ml | 559 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Mouse |
| Clonality | Recombinant Mouse Monoclonal |
| Isotype | Mouse IgG1, kappa |
| Clone Name | rNAPSA/1239 |
| Purity | Protein G affinity chromatography |
| UniProt | O96009 |
| Localization | Cytoplasmic |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT Western Blot : 2-4ug/ml |
| Limitations | This NAPSA Antibody / Secretory Pathway Antibody is available for research use only. |
|
Review this product on BioCompare and get a $20 Amazon gift card
|
Related Products
|
Napsin A (NAPSA) is a lysosomal aspartic protease primarily expressed in lung alveolar epithelial cells and renal tubular epithelium, where it functions within intracellular trafficking networks and secretory pathways. NAPSA Antibody / Secretory Pathway Antibody is designed to detect Napsin A in studies examining vesicular transport, protein localization, and compartment-specific processing. NAPSA antibody clone rNAPSA/1239, also referred to as Napsin A antibody, is widely used in investigations of epithelial cell trafficking and intracellular protein distribution.
Napsin A is localized to intracellular vesicles, including lysosomes and secretory compartments, where it participates in the processing and handling of proteins destined for secretion or degradation. Its distribution across these compartments reflects its involvement in vesicle-associated protein maturation and highlights its role in coordinating intracellular transport with enzymatic processing.
The function of Napsin A within the secretory pathway is closely linked to its role in surfactant protein maturation in lung epithelial cells. Its activity within vesicular compartments contributes to the proper folding, processing, and localization of proteins essential for pulmonary function, emphasizing its importance in epithelial cell specialization.
NAPSA antibody reagents used as secretory pathway antibodies enable detection of Napsin A within defined intracellular compartments, supporting analysis of vesicle-associated protein localization and trafficking dynamics. This provides valuable insight into how proteins are processed and transported within epithelial cells and how these processes may be altered in disease states.
The restricted expression pattern of Napsin A, with strong enrichment in lung and kidney tissues, provides a clear biological context for studying secretory pathway function. Its compartmentalized localization allows researchers to examine the relationship between intracellular trafficking, protease activity, and tissue-specific protein handling.
Overall, NAPSA antibody reagents used as secretory pathway antibodies provide insight into vesicular transport, intracellular compartmentalization, and protein trafficking, supporting research into epithelial cell biology and secretory system organization.
This antibody is part of a comprehensive NAPSA antibody collection developed to support Napsin A detection across IHC, WB, IF, and FACS applications in lung cancer and epithelial biology research.
Optimal dilution of the NAPSA Antibody / Secretory Pathway Antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
A recombinant fragment from the human protein (amino acids 189-299) was used as the immunogen for the recombinant Napsin A antibody.
Store the recombinant Napsin A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Napsin A antibody, NAPSA intracellular antibody, Secretory vesicle protease antibody, NAPSA trafficking antibody
Your bulk quote request has been submitted successfully!
Please contact us if you have any questions.
Powered by Bioz
