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Home >> Antibodies >> Recombinant MUC2 Antibody / Mucin 2

Recombinant MUC2 Antibody / Mucin 2 [clone rMLP/842] (V7968)

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  Catalog No Formulation Size Price (USD)  
Image V7968-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7968-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7968SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recmousemono
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IHC staining of FFPE human stomach with recombinant MUC2 antibody (clone rMLP/842). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human stomach with recombinant MUC2 antibody (clone rMLP/842). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human stomach with recombinant MUC2 antibody (clone rMLP/842). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant MUC2 antibody (clone rMLP/842) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG1, kappa
Clone Name rMLP/842
Purity Protein G affinity chromatography
UniProt Q02817
Localization Cell surface, cytoplasmic
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant MUC2 antibody is available for research use only.
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Description

Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.

Application Notes

Optimal dilution of the recombinant MUC2 antibody should be determined by the researcher.

Immunogen

Amino acids KYPTTTPISTTTMVTPTPTPTGTQTPTTT were used as the immunogen for this recombinant MUC2 antibody. Its epitope has been defined as GTQTP.

Storage

Store the recombinant MUC2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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