- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Recombinant MUC1 Antibody / Mucin 1 / EMA [clone r115D8] (V5491)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V5491-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 539 | |
|
|
V5491-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 249 | |
|
|
V5491SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 539 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Recombinant Mouse Monoclonal |
| Isotype | Mouse IgG2b, kappa |
| Clone Name | r115D8 |
| Purity | Protein A/G affinity |
| UniProt | P15941 |
| Localization | Cytoplasm, Cell membrane |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml |
| Limitations | This recombinant MUC1 antibody is available for research use only. |
|
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In Western blotting, it recognizes proteins in MW range of 265-400kDa, identified as different glycoforms of EMA/Mucin 1. The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. Mucin 1 may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain, which is involved in cell signaling, through phosphorylations and protein-protein interactions. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinoma tissues. Antibody to EMA/Mucin 1 is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
Optimal dilution of the recombinant MUC1 antibody should be determined by the researcher.
Recombinant full-length human Mucin 1 protein was used as the immunogen for the recombinant MUC1 antibody.
Aliquot the recombinant MUC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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