Recombinant Melan-A Antibody / Rabbit Monoclonal [clone MLANA/1761R] (V7268)

Description

MART-1/Melan-A is a protein antigen that is found on the surface of melanocytes. Antibodies against the antigen are used in the medical specialty of anatomic pathology in order to recognize cells of melanocytic differentiation, useful for the diagnosis of a melanoma. The MART-1/Melan-A antigen is specific for the melanocyte lineage, found in normal skin, the retina, and melanocytes, but not in other normal tissues. It is thus useful as a marker for melanocytic tumors (melanomas) with the caveat that it is normally found in benign nevi as well. [Wiki]

Application Notes

The optimal dilution of the recombinant Melan-A antibody for each application should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Immunogen

Human protein was used as the immunogen for this recombinant Melan-A antibody.

Storage

Store the recombinant Melan-A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).