- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Mammaglobin Antibody Rabbit Monoclonal MGB/2123R / Mammaglobin A Antibody [clone MGB/2123R] (V7306)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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V7306-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 100 ug | 559 | |
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V7306-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 20 ug | 259 | |
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V7306SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 | |
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V7306IHC-7ML | Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only* | 7 ml | 559 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG, kappa |
| Clone Name | MGB/2123R |
| Purity | Protein A affinity chromatography |
| UniProt | Q13296 |
| Localization | Cytoplasmic, cell surface, nuclear |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT |
| Limitations | This Mammaglobin antibody is available for research use only. |
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Mammaglobin A (SCGB2A2) is a secreted epithelial glycoprotein encoded by the SCGB2A2 gene and belongs to the secretoglobin family of small secreted proteins associated with mammary epithelial differentiation. Mammaglobin Antibody Rabbit Monoclonal MGB/2123R recognizes Mammaglobin A / SCGB2A2 and targets a protein widely studied as a marker of mammary epithelial cells and breast carcinoma.
Mammaglobin antibody, also referred to as Mammaglobin A antibody or SCGB2A2 antibody in the literature, detects a protein predominantly produced by luminal epithelial cells of the mammary gland. Mammaglobin A is secreted into glandular lumens as part of normal epithelial secretory activity within mammary tissue. Because of this relatively restricted tissue distribution, Mammaglobin expression has been extensively examined in studies of mammary gland biology and breast tumor origin.
Structurally, Mammaglobin A contains conserved cysteine residues characteristic of secretoglobin family proteins that contribute to stable folding within epithelial secretory pathways. As a secreted epithelial protein, Mammaglobin is typically detected within the cytoplasm of mammary epithelial cells and may also be present within glandular luminal secretions depending on tissue architecture and experimental preparation. These features make Mammaglobin an informative molecular marker for studies of epithelial differentiation and mammary gland physiology.
Expression of Mammaglobin A is frequently observed in breast epithelial cells and breast carcinoma specimens, where it reflects the differentiated state of mammary epithelial tumor cells. In breast tumors, Mammaglobin expression is often detected within epithelial tumor cell populations forming glandular structures, while surrounding stromal cells and connective tissue elements generally show little to no staining. These expression patterns have made Mammaglobin an important protein target in breast cancer research and epithelial tumor characterization.
Mammaglobin Antibody Rabbit Monoclonal (clone MGB/2123R) is developed to detect Mammaglobin A / SCGB2A2 in protein expression studies involving mammary epithelial tissues and breast cancer models. Antibodies targeting Mammaglobin are commonly used to investigate epithelial differentiation, tumor cell identity, and Mammaglobin expression patterns in mammary gland biology and breast tumor research.
Optimal dilution of the Mammaglobin Antibody Rabbit Monoclonal MGB/2123R should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Full length recombinant human protein was used as the immunogen for the recombinant Mammaglobin antibody.
Store the Mammaglobin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Mammaglobin A antibody, SCGB2A2 antibody, Mammaglobin breast marker antibody, Secretoglobin family 2A member 2 antibody, Mammary gland secretoglobin antibody
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