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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Recombinant KRT5 Antibody rKRT5/6969 recognizes a protein of 58kDa, which is identified as Cytokeratin 5 (KRT5). This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia, yoepithelial, and mesothelium. Anti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas express. Anti-KRT5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled with anti-KRT5.
Explore our protein microarray-validated Cytokeratin 5 Antibody KRT5/3594 for investigating basal epithelial differentiation, squamous cell carcinomas, and keratin filament organization.
Optimal dilution of the Recombinant KRT5 Antibody rKRT5/6969 should be determined by the researcher.
A recombinant partial protein sequence (within amino acids 390-590) from the human protein was used as the immunogen for the Recombinant KRT5 Antibody rKRT5/6969.
Aliquot the Recombinant KRT5 Antibody rKRT5/6969 and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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