- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Kallikrein 7 Antibody Recombinant Rabbit MAb KLK7/8971R / KLK7 [clone KLK7/8971R] (V4652)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V4652-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
|
|
V4652-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
|
|
V4652SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG, kappa |
| Clone Name | KLK7/8971R |
| Purity | Protein A/G affinity |
| UniProt | P49862 |
| Localization | Secreted |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT |
| Limitations | This Kallikrein 7 antibody is available for research use only. |
|
Review this product on BioCompare and get a $20 Amazon gift card
|
Related Products
|
Kallikrein related peptidase 7 (KLK7) is a secreted serine protease that belongs to the human kallikrein family of trypsin-like enzymes and plays an important role in epidermal homeostasis. KLK7 is highly expressed in differentiated keratinocytes of the epidermis and contributes to the controlled degradation of corneodesmosomal proteins that maintain adhesion between corneocytes. This proteolytic activity is essential for normal desquamation and skin barrier turnover. Kallikrein 7 Antibody Recombinant Rabbit MAb clone KLK7/8971R recognizes this epidermal protease and enables detection of KLK7 expression in studies examining epidermal differentiation and skin biology.
KLK7 is also commonly referred to as stratum corneum chymotryptic enzyme (SCCE) and functions as a chymotrypsin-like protease involved in the regulated shedding of corneocytes from the outermost layer of the skin. Expression of KLK7 is tightly controlled within the epidermis and is primarily localized to the upper layers of the stratified epithelium where terminal keratinocyte differentiation occurs. Antibodies directed against KLK7 allow researchers to examine epidermal structure, keratinocyte maturation, and mechanisms governing skin barrier maintenance.
Kallikrein 7 has been implicated in several dermatological conditions in which epidermal barrier function and protease activity are altered. Dysregulated KLK7 activity has been associated with inflammatory skin diseases and abnormal desquamation processes. Because of its role in epidermal physiology, detection of KLK7 expression is valuable in studies of skin biology, keratinocyte differentiation, and epithelial tissue remodeling.
Kallikrein 7 Antibody Recombinant Rabbit MAb clone KLK7/8971R is designed to recognize KLK7 in epithelial tissues and biological samples used for dermatological and epithelial research. The antibody supports investigation of KLK7 expression patterns in skin tissue, epithelial structures, and experimental models examining epidermal differentiation.
Detection of KLK7 using Kallikrein 7 Antibody Recombinant Rabbit MAb (clone KLK7/8971R) enables analysis of epidermal protease expression and supports research investigating skin barrier function, keratinocyte biology, and the molecular regulation of desquamation in epithelial tissues.
Optimal dilution of the Kallikrein 7 Antibody Recombinant Rabbit MAb KLK7/8971R should be determined by the researcher.
A recombinant fragment of human KLK7 protein (within amino acids 1-200) was used as the immunogen for the recombinant Kallikrein 7 antibody.
Aliquot the Kallikrein 7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
KLK7 antibody, Stratum corneum chymotryptic enzyme antibody, SCCE antibody, Human kallikrein 7 antibody, PRSS6 antibody
Your bulk quote request has been submitted successfully!
Please contact us if you have any questions.
Powered by Bioz
