- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
INHA Antibody Recombinant Mouse MAb rINHA/6919 / Inhibin alpha INHA Antibody [clone rINHA/6919] (V9664)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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V9664-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
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V9664-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
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V9664SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Mouse |
| Clonality | Recombinant Mouse Monoclonal |
| Isotype | Mouse IgG1, kappa |
| Clone Name | rINHA/6919 |
| Purity | Protein A/G affinity |
| UniProt | P05111 |
| Localization | Cytoplasm, Nucleus |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml Western Blot : 2-4ug/ml |
| Limitations | This recombinant INHA antibody is available for research use only. |
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Inhibin subunit alpha (INHA) is a secreted glycoprotein hormone component encoded by the INHA gene and produced primarily by granulosa cells of the ovary and Sertoli cells of the testis. The protein is commonly referred to as Inhibin alpha and forms part of the heterodimeric hormones inhibin A and inhibin B. INHA Antibody Recombinant Mouse MAb rINHA/6919 recognizes the INHA protein and enables detection of inhibin alpha expression in studies examining reproductive biology and endocrine related tumors.
Inhibins belong to the transforming growth factor beta (TGF beta) superfamily of signaling molecules. The inhibin alpha subunit associates with either the beta A or beta B subunit to form inhibin A or inhibin B respectively. These hormones function as endocrine regulators that suppress secretion of follicle stimulating hormone (FSH) from the anterior pituitary gland, thereby contributing to regulation of gonadal endocrine signaling and reproductive physiology.
In normal tissues, INHA expression is most prominent in ovarian granulosa cells and testicular Sertoli cells. The protein is synthesized as a precursor molecule that undergoes proteolytic processing before secretion. Through its endocrine function, inhibin alpha participates in the feedback regulation of reproductive hormone signaling and contributes to the control of follicular development and spermatogenesis.
Expression of inhibin alpha has also been reported in several tumor types derived from endocrine or steroidogenic cell populations. INHA expression has been observed in ovarian granulosa cell tumors, other sex cord stromal tumors, and certain adrenal cortical tumors. Detection of inhibin alpha protein therefore supports research investigating endocrine tumor biology and differentiation of steroid producing tissues.
INHA Antibody Recombinant Mouse MAb rINHA/6919 provides a reagent for detecting INHA protein in studies of gonadal development, reproductive hormone signaling, and endocrine tumor biology. Recombinant monoclonal antibodies recognize a defined epitope within the target antigen, enabling consistent antigen recognition while supporting investigation of inhibin alpha expression in molecular and cellular research systems.
Optimal dilution of the INHA Antibody Recombinant Mouse MAb rINHA/6919 should be determined by the researcher.
A portion of amino acids 233-362 was used as the immunogen for the recombinant INHA antibody.
Aliquot the recombinant INHA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Inhibin alpha antibody, INHA antibody, Inhibin alpha subunit antibody, Inhibin A alpha antibody
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