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- Email: info@nsjbio.com
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This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Optimal dilution of the recombinant IL1 beta antibody should be determined by the researcher.
A recombinant protein fragment was used as the immunogen for the recombinant IL1 beta antibody.
Aliquot the recombinant IL1 beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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