Human IgG Antibody IG507R / Rabbit Monoclonal [clone IG507R] (V7251)

Description

Human IgG Antibody IG507R is a rabbit monoclonal antibody developed for the specific detection of human immunoglobulin G, the predominant antibody class in human serum and extracellular fluids. Human IgG is composed of two gamma heavy chains and two light chains that together mediate antigen recognition and numerous immune effector functions, including complement activation, opsonization, and Fc receptor engagement. The rabbit monoclonal format of clone IG507R provides excellent specificity, sensitivity, and lot-to-lot consistency, making Human IgG Antibody IG507R a dependable reagent for immunological and biomedical research. NSJ Bioreagents supplies this antibody for reliable detection of human IgG across a wide range of laboratory applications.

Human IgG is produced by plasma cells following antigen stimulation and class-switch recombination and represents the major immunoglobulin class responsible for long-term humoral immunity. It plays an essential role in neutralizing pathogens, promoting phagocytosis, activating the classical complement pathway, and mediating antibody-dependent cellular cytotoxicity. Because of its abundance and biological importance, Human IgG Antibody IG507R is widely used to identify plasma cells, evaluate antibody production, and characterize immune responses in normal and diseased tissues.

Rabbit monoclonal antibodies are valued for their high affinity, excellent epitope recognition, and reproducible performance across multiple experimental applications. These characteristics make clone IG507R well suited for immunohistochemistry, Western blotting, and related immunodetection techniques requiring robust and consistent staining. Human IgG Antibody IG507R is particularly useful in studies of lymphoid tissues, plasma cell neoplasms, chronic inflammation, autoimmune disease, infectious disease, and therapeutic antibody development, where accurate detection of human immunoglobulin G is critical.

Human IgG Antibody IG507R provides reliable detection of human immunoglobulin G in studies of humoral immunity, plasma cell biology, antibody production, and immune-mediated disease. The rabbit monoclonal format of clone IG507R delivers the specificity and reproducibility required for high-quality immunological research across diverse experimental systems.

Explore our Human IgG Antibody page for additional antibodies supporting sensitive and specific detection of human IgG across a wide range of immunological research applications.

Application Notes

The optimal dilution of the Human IgG Antibody IG507R for each application should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Immunogen

Human Ig Gamma Chain was used as the immunogen for this Human IgG Antibody IG507R.

Storage

Store the Human IgG Antibody IG507R at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Alternate Names

IGHG1 antibody, Immunoglobulin G antibody, Human Immunoglobulin G antibody, Ig Gamma Heavy Chain antibody, Human IgG Heavy Chain antibody, Immunoglobulin Gamma antibody