- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Recombinant Human IgG antibody provides a reliable tool for detecting human immunoglobulin G, the most abundant antibody isotype in circulation. IgG plays a central role in adaptive immunity, where it mediates pathogen neutralization, complement activation, and antibody dependent cellular cytotoxicity. Because of its prevalence and functional diversity, human IgG is routinely studied in immunology, infectious disease, and therapeutic antibody research.
IgG is composed of two heavy chains and two light chains, forming a Y shaped molecule with variable antigen binding regions and a constant Fc region. The Fc region interacts with immune receptors and complement proteins, enabling IgG to direct immune effector functions. Different subclasses of IgG (IgG1, IgG2, IgG3, and IgG4) contribute unique properties to immune defense, influencing flexibility, half life, and effector activity.
The Recombinant Human IgG antibody clone rIG266 offers specific detection of human IgG with consistent performance. Recombinant production eliminates variability between lots, making it well suited for quantitative studies and clinical research. Clone rIG266 has been employed to monitor IgG levels in serum, evaluate vaccine responses, and validate therapeutic antibody production. Its reproducibility ensures accuracy across a range of applications.
Research using clone rIG266 has supported investigations into antibody mediated immunity, autoimmune disease, and monoclonal antibody therapy. IgG is widely monitored as a biomarker of immune status and is also a key molecule in biopharmaceutical development. This antibody has contributed to reliable detection of IgG in both laboratory and translational settings.
NSJ Bioreagents provides this Recombinant Human IgG antibody to enable high quality studies of immune function and antibody biology. Human IgG is also referred to as immunoglobulin G antibody, gamma globulin antibody, IgG heavy chain antibody, and Fc gamma receptor binding antibody, illustrating the varied contexts in which it is studied.
The optimal dilution of the recombinant human IgG antibody for each application should be determined by the researcher.
Human Ig Gamma Chain was used as the immunogen for this recombinant human IgG antibody.
Store the recombinant human IgG antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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