- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Human IgD Antibody for ELISA / Biotinylated IgD B Cell Marker Detection Antibody [clone RM123] (R20185BTN)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
R20185BTN-50UG | 1 mg/ml in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide | 50 ug | 439 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Biotin Conjugate |
| Host | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | RM123 |
| Purity | Protein A purified from animal origin-free supernatant |
| UniProt | P01880 |
| Gene ID | 3495 |
| Applications | ELISA : 25ng/well-200ng/well (Capture); 0.01-0.1ug/ml (Detection) |
| Limitations | This Human IgD Antibody for ELISA / Biotinylated IgD B Cell Marker Detection Antibody is available for research use only. |
|
Review this product on BioCompare and get a $20 Amazon gift card
|
Related Products
|
Human immunoglobulin delta (IGHD) encodes the heavy chain constant region of IgD, an immunoglobulin isotype primarily expressed on the surface of naive B cells as part of the B cell receptor complex. IgD is co-expressed with IgM during early stages of B cell development and contributes to antigen recognition, signal transduction, and regulation of B cell activation. This co-expression defines the naive B cell phenotype and is critical for maintaining immune surveillance prior to class switching and differentiation into antibody-secreting cells.
Human IgD Antibody for ELISA / Biotinylated IgD B Cell Marker Detection Antibody is engineered for enhanced sensitivity and selective detection of IgD in ELISA workflows utilizing streptavidin-based signal amplification systems. Human IgD antibody, also referred to as anti-IGHD antibody or IgD immunoglobulin antibody, enables detection of IgD in biological samples and supports analysis of B cell-associated immune responses. This biotinylated recombinant rabbit monoclonal antibody clone RM123 provides selective recognition of human IgD while enabling amplified signal generation for improved assay performance in low-abundance detection scenarios.
In sandwich ELISA configurations, biotinylated detection antibodies provide increased assay sensitivity and expanded dynamic range through streptavidin-mediated amplification. The Human IgD Antibody for ELISA / Biotinylated IgD B Cell Marker Detection Antibody binds selectively to IgD, allowing accurate detection even at low analyte concentrations where conventional detection approaches may be limited. This is particularly important in studies of B cell maturation, immune profiling, and early-stage immune responses where IgD levels are tightly regulated and relatively low.
Clone RM123 antibody recognizes human IgD, ensuring selective detection without cross-reactivity to other immunoglobulin classes such as IgG, IgA, IgM, or IgE. The recombinant rabbit monoclonal format provides strong affinity, consistent performance, and reproducibility across ELISA platforms. Biotin conjugation enhances assay flexibility by enabling compatibility with streptavidin-based detection systems commonly used in ELISA assays.
Measurement of IgD using biotinylated detection antibodies is widely applied in immunology research, particularly in studies of naive B cell populations, immune regulation, and mucosal immune responses. IgD has also been implicated in interactions with innate immune cells, suggesting a broader role in immune modulation beyond its classical function as a B cell receptor component. Because IgD expression reflects early-stage immune activity and B cell biology, accurate detection provides valuable insight into immune function and antibody dynamics. This antibody supports these applications by enabling sensitive and reliable detection of IGHD-containing immunoglobulins in ELISA-based systems requiring enhanced signal amplification, high specificity, and consistent performance.
This antibody is part of a broader immunoglobulin detection antibody collection, including reagents for Ig classes and light chains across multiple species and immunoassay formats.
The stated application concentrations are suggested starting points. Titration of the Human IgD Antibody for ELISA / Biotinylated IgD B Cell Marker Detection Antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Human IgD was used as the immunogen for this biotinylated recombinant Human IgD antibody.
Store the Human IgD antibody at -20oC.
Biotin IgD antibody, Biotinylated IGHD antibody, Human IgD biotin ELISA antibody, IgD detection biotin antibody, IgD B cell marker biotin antibody
Your bulk quote request has been submitted successfully!
Please contact us if you have any questions.
Powered by Bioz
