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Home >> Antibodies >> Recombinant FSH beta Antibody

Recombinant FSH beta Antibody [clone FSHb/2033R] (V9140)

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  Catalog No Formulation Size Price (USD)  
Image V9140-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 559
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V9140-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 259
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V9140SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 559
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FSHB Antibody Recombinant Pituitary IHC. Immunohistochemistry staining of FFPE human pituitary tissue using recombinant monoclonal clone FSHb/2033R demonstrates extensive granular cytoplasmic HRP-DAB brown staining within anterior pituitary endocrine cell populations, consistent with Follicle stimulating hormone beta / FSHB localization in hormone-secreting gonadotroph cells. The dense punctate staining pattern reflects accumulation of secretory hormone-associated protein within pituitary endocrine compartments. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant FSH beta antibody (clone FSHb/2033R) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Host Rabbit
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name FSHb/2033R
Purity Protein A/G affinity
UniProt P01225
Localization Cytoplasmic, secreted
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant FSH beta antibody is available for research use only.
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Description

This MAb reacts with a protein of 22kDa, identified as beta sub-unit of FSH. It does not cross react with the alpha sub-unit. Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.

For additional reproductive hormone and pituitary signaling research antibodies targeting gonadotroph markers and endocrine-associated cellular pathways, explore the broader FSHB Antibody page featuring monoclonal clone FLTPb-1.

Application Notes

Optimal dilution of the recombinant FSH beta antibody should be determined by the researcher.

Immunogen

Recombinant hFSH beta sub-unit was used as the immunogen for the recombinant FSH beta antibody.

Storage

Aliquot the recombinant FSH beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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