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Home >> Antibodies >> Recombinant Frataxin Antibody / FXN

Recombinant Frataxin Antibody / FXN [clone rFXN/2124] (V7790)

  Catalog No Formulation Size Price (USD)  
Image V7790-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7790-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7790SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recmousemono
Bulk quote request
SDS-PAGE analysis of purified, BSA-free recombinant FXN antibody (clone rFXN/2124) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG1, kappa
Clone Name rFXN/2124
Purity Protein G affinity chromatography
UniProt Q16595
Localization Cytoplasmic
Applications ELISA (order BSA-free format for coating) :
Limitations This recombinant Frataxin antibody is available for research use only.
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Description

Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.

Application Notes

Optimal dilution of the recombinant Frataxin antibody should be determined by the researcher.

Immunogen

Amino acids 57-210 from the human protein were used as the immunogen for this FXN antibody.

Storage

Store the recombinant Frataxin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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