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Home >> Antibodies >> Recombinant FABP1 Antibody / Fatty Acid Binding Protein 1

Recombinant FABP1 Antibody / Fatty Acid Binding Protein 1 [clone rFABP1/8520] (V4873)

  Catalog No Formulation Size Price (USD)  
Image V4873-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V4873-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V4873SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recmousemono
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IHC staining of FFPE human kidney tissue with recombinant FABP1 antibody (clone rFABP1/8520). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant FABP1 antibody (clone rFABP1/8520) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG1, kappa
Clone Name rFABP1/8520
Purity Protein A/G affinity
UniProt P07148
Localization Cytoplasm, Nucleus
Applications Western blot : 2-4ug/ml
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Limitations This recombinant FABP1 antibody is available for research use only.
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Description

Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.

Application Notes

Optimal dilution of the recombinant FABP1 antibody should be determined by the researcher.

Immunogen

A recombinant partial protein sequence (within amino acids 1-127) from the human protein was used as the immunogen for the recombinant FABP1 antibody.

Storage

Aliquot the recombinant FABP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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