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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.
Optimal dilution of the recombinant FABP1 antibody should be determined by the researcher.
A recombinant partial protein sequence (within amino acids 1-127) from the human protein was used as the immunogen for the recombinant FABP1 antibody.
Aliquot the recombinant FABP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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