Desmin Antibody / Muscle Cytoskeleton Protein [clone rDES/1711] (V9768)

Desmin Antibody Uterus IHC. Immunohistochemistry staining of FFPE human uterus tissue using Desmin antibody (clone rDES/1711) demonstrates strong, diffuse cytoplasmic staining of smooth muscle cells, consistent with the abundant expression of Desmin within uterine smooth muscle tissue. Desmin is a type III intermediate filament protein that forms a major component of the muscle cytoskeleton, providing structural support and helping maintain the organization of contractile elements within muscle cells. The robust staining pattern observed throughout smooth muscle bundles is consistent with the established role of Desmin as a marker of muscle differentiation and contractile tissue identity. Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min.

Desmin Antibody Human Uterus Tissue IHC. Immunohistochemistry staining of FFPE human uterus tissue using Desmin antibody (clone rDES/1711) demonstrates strong cytoplasmic staining throughout smooth muscle cell populations, consistent with the abundant expression of Desmin in contractile uterine tissue. Desmin is a type III intermediate filament protein that forms an essential component of the muscle cytoskeleton, helping maintain cellular architecture and mechanical integrity within smooth muscle cells. The widespread immunoreactivity observed within smooth muscle bundles is consistent with the established role of Desmin as a marker of muscle differentiation and smooth muscle tissue identity. Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min.

SDS-PAGE Analysis of Purified, BSA-Free recombinant Desmin Antibody (clone rDES/1711). Confirmation of Integrity and Purity of the Antibody.

Desmin Antibody Multi-Species Heart WB. Western blot analysis of heart tissue lysates from human, mouse, rat, hamster, guinea pig, and rabbit using Desmin Antibody (clone rDES/1711) detects a band at approximately 53 kDa across all species, consistent with the expected molecular weight of Desmin. The conserved banding pattern supports reliable cross-species detection of this muscle-specific intermediate filament protein, aligning with its role as a structural marker of muscle cells and tissue integrity.

Desmin Antibody Human Tissue Panel WB. Western blot analysis of human heart, human intestine, and RH30 cell lysates using Desmin Antibody (clone rDES/1711) detects a band at approximately 53 kDa, consistent with the expected molecular weight of Desmin. The presence of signal in heart and intestine tissues, as well as rhabdomyosarcoma cells, supports detection of this muscle-associated intermediate filament protein, aligning with its role in muscle structure and differentiation.