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Alpha-catenin and beta-catenin bind to the intracellular domain of E-cadherin while p120 catenin (delta-1-catenin) binds E-cadherin at a juxta-membrane site. The complex stabilizes tight junctions. In the cell, delta-1-catenin localized to the E-cadherin/catenins cell adhesion complex, directly associates with cytoplasmic C-terminus of E-cadherin and may similarly interact with other cadherins.
Optimal dilution of the recombinant Delta 1 Catenin antibody should be determined by the researcher.
A portion of amino acids 900-1,000 was used as the immunogen for the recombinant Delta 1 Catenin antibody.
Aliquot the recombinant Delta 1 Catenin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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