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Home >> Antibodies >> Recombinant CDX2 Antibody

Recombinant CDX2 Antibody [clone rCDX2/1690] (V7661)

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  Catalog No Formulation Size Price (USD)  
Image V7661-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7661-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7661SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recmousemono
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IHC testing of FFPE human colon with recombinant CDX2 antibody (clone rCDX2/1690). HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min followed by cooling prior to testing.
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IHC testing of FFPE human colon with recombinant CDX2 antibody (clone rCDX2/1690). HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min followed by cooling prior to testing.
IHC testing of FFPE human colon with recombinant CDX2 antibody (clone rCDX2/1690). HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min followed by cooling prior to testing.
SDS-PAGE analysis of purified, BSA-free recombinant CDX2 antibody (clone rCDX2/1690) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG1, kappa
Clone Name rCDX2/1690
Purity Protein G affinity chromatography
UniProt Q99626
Localization Nuclear
Applications ELISA (order BSA-free format for coating) :
Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant CDX2 antibody is available for research use only.
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Description

The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoidsand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma.However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

Application Notes

Optimal dilution of the recombinant CDX2 antibody should be determined by the researcher.

Immunogen

Amino acids 150-249 from the human protein were used as the immunogen for this recombinant CDX2 antibody.

Storage

Store the recombinant CDX2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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