- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CD5 Antibody / Adaptive Immune Response Marker Antibody [clone C5/8117R] (V4168)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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V4168-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
|
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V4168-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
|
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V4168SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG, kappa |
| Clone Name | C5/8117R |
| Purity | Protein A/G affinity |
| UniProt | P06127 |
| Localization | Cell surface |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT |
| Limitations | This CD5 Antibody / Adaptive Immune Response Marker Antibody is available for research use only. |
|
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CD5 (CD5 molecule) is a type I transmembrane glycoprotein of the scavenger receptor cysteine-rich (SRCR) superfamily, expressed on T lymphocytes and a subset of B cells involved in antigen-driven immune responses. CD5 Antibody / Adaptive Immune Response Marker Antibody is used to detect CD5 in the context of adaptive immunity, where it contributes to the regulation, amplification, and fine-tuning of antigen-specific lymphocyte responses. CD5 antibody, also known as T cell surface glycoprotein CD5 antibody or LEU1 antibody, is widely used to study T cell-mediated immunity and adaptive immune system dynamics.
Adaptive immune responses depend on precise recognition of antigen and subsequent activation of T lymphocytes through the T cell receptor. CD5 plays a key role in modulating these signaling events by adjusting activation thresholds and shaping the strength of downstream responses. Because CD5 influences how T cells interpret antigenic signals, its expression provides important context for understanding immune response magnitude, sensitivity, and specificity. CD5 antibody is therefore frequently used in studies examining antigen recognition, signal integration, and functional immune responses.
CD5-positive T lymphocytes are central to adaptive immunity, participating in clonal expansion, differentiation into effector and memory subsets, and coordination of immune responses across tissues. Detection of CD5 enables identification of these populations within lymphoid organs, peripheral tissues, and experimental systems, supporting analysis of immune activation, proliferation, and long-term immune memory formation. CD5 antibody is particularly useful for studying how adaptive immune responses evolve over time and how lymphocytes respond to repeated or sustained antigen exposure.
In addition to T cells, CD5 expression on certain B cell subsets contributes to adaptive immune regulation, particularly in contexts involving antibody production and immune modulation. These CD5-positive B cells may play roles in regulating immune responses and maintaining balance within the adaptive immune system. CD5 antibody enables detection of these populations, providing a broader view of adaptive immunity beyond T cell biology alone.
CD5 is also relevant in disease settings where adaptive immune responses are altered, including infection, autoimmune disease, and cancer. Changes in CD5 expression or signaling can influence the effectiveness and regulation of immune responses, making CD5 antibody a valuable tool for studying disease-associated immune dynamics and therapeutic intervention strategies.
This antibody is suitable for detecting CD5 in research applications focused on adaptive immunity and antigen-driven responses. Its ability to identify CD5-positive lymphocytes supports studies of immune response mechanisms, antigen recognition, and lymphocyte functional behavior.
Because CD5 is closely linked to adaptive immune responses, CD5 antibody is widely used in studies of T cell-mediated immunity, antigen-specific activation, and immune system function.
A full range of CD5 antibody reagents for immunohistochemistry, western blot, and flow cytometry is available on our CD5 Antibody collection page.
Optimal dilution of the CD5 Antibody / Adaptive Immune Response Marker Antibody should be determined by the researcher.
Recombinant protein corresponding to the extracellular domain of human CD5 was used as the immunogen for the recombinant CD5 antibody.
Aliquot the recombinant CD5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
CD5 adaptive immunity antibody, CD5 adaptive immune marker antibody, CD5 T cell response antibody, CD5 antigen response marker antibody, CD5 immune response antibody
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