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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Recombinant CD47 Antibody rCD47/6589 reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
For a Protein Microarray Validated antibody targeting the same protein, see our CD47 Antibody CD47/2937 / IAP Monoclonal Antibody.
Optimal dilution of the Recombinant CD47 Antibody rCD47/6589 should be determined by the researcher.
Recombinant full-length human protein was used as the immunogen for the Recombinant CD47 Antibody rCD47/6589.
Aliquot the Recombinant CD47 Antibody rCD47/6589 and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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