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Home >> Antibodies >> Recombinant CD31 Antibody / PECAM-1

Recombinant CD31 Antibody / PECAM-1 [clone rC31.3] (V8000)

  Catalog No Formulation Size Price (USD)  
Image V8000-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V8000-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V8000SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recmousemono
Bulk quote request
Western blot testing of human THP-1 cell lysate with recombinant CD31 antibody (clone rC31.3). Expected molecular weight: 83-130 kDa depending on level of glycosylation.
SDS-PAGE analysis of purified, BSA-free recombinant CD31 antibody (clone rC31.3) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG1, kappa
Clone Name rC31.3
Purity Protein G affinity chromatography
Localization Cell surface, cytoplasmic
Applications Western blot : 1-2ug/ml
Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant CD31 antibody is available for research use only.
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Description

CD31, also called PECAM-1, is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. It is expressed by stem cells of the hematopoietic system and CD31 antibody can be used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. CD31 antibody has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. This antibody reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high expression level may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

Application Notes

Optimal dilution of the recombinant CD31 antibody should be determined by the researcher.

Immunogen

Recombinant human protein

Storage

Store the recombinant CD31 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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