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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.
Optimal dilution of the recombinant CD27 antibody should be determined by the researcher.
Recombinant human full-length protein was used as the immunogen for the recombinant CD27 antibody.
Aliquot the recombinant CD27 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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