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Home >> Antibodies >> Recombinant CD209 Antibody / DC-SIGN

Recombinant CD209 Antibody / DC-SIGN [clone rC209/1781] (V7840)

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  Catalog No Formulation Size Price (USD)  
Image V7840-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7840-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7840SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recmousemono
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IHC staining of FFPE human colon carcinoma with recombinant CD209 antibody (clone rC209/1781). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
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IHC staining of FFPE human colon carcinoma with recombinant CD209 antibody (clone rC209/1781). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
IHC staining of FFPE human colon carcinoma with recombinant CD209 antibody (clone rC209/1781). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant CD209 antibody (clone rC209/1781) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG1, kappa
Clone Name rC209/1781
Purity Protein G affinity chromatography
UniProt Q9NNX6
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant CD209 antibody is available for research use only.
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Description

DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.

Application Notes

Optimal dilution of the recombinant CD209 antibody should be determined by the researcher.

Immunogen

A human recombinant partial protein was used as the immunogen for this recombinant CD209 antibody.

Storage

Store the recombinant CD209 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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