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Home >> Antibodies >> Recombinant CD137 Antibody / 4-1BB / TNFRSF9

Recombinant CD137 Antibody / 4-1BB / TNFRSF9 [clone 4-1BB/4552R] (V8061)

  Catalog No Formulation Size Price (USD)  
Image V8061-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V8061-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V8061SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recrabbitmono
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IHC staining of FFPE human kidney with CD137 antibody (clone 4-1BB/4552R). HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
IHC staining of FFPE human kidney with CD137 antibody (clone 4-1BB/4552R). HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name 4-1BB/4552R
Purity Protein A affinity chromatography
UniProt Q07011
Localization Cell surface, cytoplasmic
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Limitations This recombinant CD137 antibody is available for research use only.
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Description

CD137 belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. It is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. CD137 antibody may improve cancer treatment, and has been implicated in breast cancer, melanoma and lymphoma.

Application Notes

Optimal dilution of the recombinant CD137 antibody should be determined by the researcher.

Immunogen

A human CD137 protein fragment within amino acids 19-188 was used as the immunogen for the recombinant CD137 antibody.

Storage

Store the recombinant CD137 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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