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Home >> Antibodies >> Recombinant CALB2 Antibody / Calretinin

Recombinant CALB2 Antibody / Calretinin [clone rCALB2/7123] (V4448)

  Catalog No Formulation Size Price (USD)  
Image V4448-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V4448-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V4448SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recmousemono
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IHC staining of FFPE human brain tissue with recombinant CALB2 antibody (clone rCALB2/7123). Inset: PBS instead of primary (secondary negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG1, kappa
Clone Name rCALB2/7123
Purity Protein A affinity
UniProt P22676
Localization Cytoplasm, Nucleus
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT
Limitations This recombinant CALB2 antibody is available for research use only.
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Description

It recognizes a protein of about 29kDa, which is identified as Calretinin (also known as Calbindin 2). Calretinin is a vitamin D-dependent calcium-binding protein involved in calcium signaling. It is present in subsets of neurons throughout the brain and spinal chord, including sensory ganglia. Antibody to calretinin is useful in differentiating mesothelioma from adenocarcinomas of the lung. It also aids in differentiating adrenal cortical neoplasms from pheochromocytomas.

Application Notes

Optimal dilution of the recombinant CALB2 antibody should be determined by the researcher.

Immunogen

A recombinant human protein fragment (within amino acids 23-242) was used as the immunogen for the recombinant CALB2 antibody.

Storage

Aliquot the recombinant CALB2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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