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Home >> Antibodies >> Recombinant BAX Antibody

Recombinant BAX Antibody [clone BAX/3158R] (V5783)

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  Catalog No Formulation Size Price (USD)  
Image V5783-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 559
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V5783-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 259
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V5783SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 559
Microvalidated Recrabbitmono
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Western blot testing of human A549 and MCF7 cell lysate with recombinant BAX antibody (clone BAX/3158R). Predicted molecular weight ~21 kDa.
Western blot testing of human A549 cell lysate with recombinant BAX antibody (clone BAX/3158R). Predicted molecular weight ~21 kDa.
SDS-PAGE analysis of purified, BSA-free recombinant BAX antibody (clone BAX/3158R) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Host Rabbit
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name BAX/3158R
UniProt Q07812
Localization Cytoplasm
Applications Western Blot : 2-4ug/ml
Limitations This recombinant BAX antibody is available for research use only.
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Description

Recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.

Learn more about Bax biology and explore our highly published mouse monoclonal Bax antibody on our Bax Antibody page.

Application Notes

Optimal dilution of the recombinant BAX antibody should be determined by the researcher.

Immunogen

A portion of amino acids 1-100 from human BAX protein was used as the immunogen for the recombinant BAX antibody.

Storage

Aliquot the recombinant BAX antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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