- Tel: 858.663.9055
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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Recognizes a protein of 21kDa, identified as the Bax protein. This mAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Optimal dilution of the recombinant Bax antibody should be determined by the researcher.
Recombinant full-length human BAX protein was used as the immunogen for the recombinant Bax antibody.
Aliquot the recombinant Bax antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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