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Home >> Antibodies >> Recombinant Aciculin Antibody / Phosphoglucomutase 5 / PGM5

Recombinant Aciculin Antibody / Phosphoglucomutase 5 / PGM5 [clone PGM5/7005R] (V9416)

  Catalog No Formulation Size Price (USD)  
Image V9416-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V9416-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V9416SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recrabbitmono
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IHC staining of FFPE human prostate tissue with recombinant Aciculin antibody (clone PGM5/7005R) at 2ug/ml. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant Aciculin antibody (clone PGM5/7005R) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name PGM5/7005R
Purity Protein A/G affinity
UniProt Q15124
Localization Cytoplasm
Applications Immunohistochemistry (FFPE) : 2-4ug/ml
Limitations This recombinant Aciculin antibody is available for research use only.
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Description

Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.

Application Notes

Optimal dilution of the recombinant Aciculin antibody should be determined by the researcher.

Immunogen

Cytoskeletal fraction of the human myometrium tissue extract was used as the immunogen for the recombinant Aciculin antibody.

Storage

Aliquot the recombinant Aciculin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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