- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
RAVER2 Antibody / Ribonucleoprotein PTB-binding 2 [clone 29R51] (RQ8867)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
RQ8867 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 439 |
|
| Availability | 1-2 days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | 29R51 |
| Purity | Affinity chromatography |
| UniProt | Q9HCJ3 |
| Applications | Western Blot : 1:500-1:2000 |
| Limitations | This RAVER2 antibody is available for research use only. |
|
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|
RAVER2 is known to bind to polypyrimidine tracts in target RNAs, facilitating the recruitment of other hnRNP proteins and RNA-binding factors. This interaction enables RAVER2 to influence alternative splicing, mRNA stability, and translation efficiency of target transcripts. By modulating these processes, RAVER2 plays a crucial role in shaping the transcriptome and proteome of cells. Moreover, studies have shown that RAVER2 is involved in the regulation of key signaling pathways, such as the PI3K/Akt/mTOR pathway and the Wnt/β-catenin pathway. Dysregulation of RAVER2 expression has been linked to various diseases, including cancer, neurodevelopmental disorders, and autoimmune conditions. Recent research has shed light on the crosstalk between RAVER2 and other RNA-binding proteins, such as PTB (polypyrimidine tract-binding protein) and hnRNP A1. These interactions form intricate regulatory networks that coordinate gene expression in response to cellular cues.
Optimal dilution of the RAVER2 antibody should be determined by the researcher.
A synthetic peptide specific to human RAVER2 protein was used as the immunogen for the RAVER2 antibody.
Store the RAVER2 antibody at -20oC.
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