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- Tel: 858.663.9055
- Email: info@nsjbio.com
The RARB gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [RefSeq]
Optimal dilution of the RARB antibody should be determined by the researcher.
A synthetic peptide specific to human Retinoic Acid Receptor beta / RARB was used as the immunogen for the RARB antibody.
Store the RARB antibody at -20oC.
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