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- Tel: 858.663.9055
- Email: info@nsjbio.com
Rap guanine nucleotide exchange factor 2 is a protein that in humans is encoded by the RAPGEF2 gene. Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation.
Optimal dilution of the RAPGEF2 antibody should be determined by the researcher.
A human recombinant partial protein (amino acids S1266-V1499) was used as the immunogen for the RAPGEF2 antibody.
After reconstitution, the RAPGEF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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